Persistently elevated hoof wall surface temperatures in the feet of all horses with insulin-induced laminitis, suggesting vasodilation, but found that causing persistent vasodilation in the foot with a vasodilator other than insulin did not cause laminitis. No suggestion of hypoperfusion or thromboembolism.
It may be that the different forms of laminitis have very different pathologies in the foot, and therefore treatments for one may be unsuitable for another.
On this limited evidence, given that many cases of laminitis have some rotation and/or distal descent of P3 and therefore the possibility of haemorrhage, and that laminitis due to hyperinsulinaemia (the majority of laminitis cases) is likely to involve vasodilation rather than vasoconstriction, the use of Aspirin would appear to be contra-indicated.
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